Somatic Gene Therapy Essay -- Genetics Science Ethics Essays

Somatic Gene Therapy To a parent, the thought of their child having a severe, yet rare genetic disease brings guilt, sadness, and responsibility to an aching heart. Parents who see their child pass through life with the weight of a terminal illness often wish in their hearts that the curse had been placed upon them rather than their child. To some, the thought of the old clichà © "no parent ought to see their child die" seems to swim endlessly in their mind. The hope for a cure fills the hearts of many waiting on the edge of their seats in hopes for a better quality of life for themselves, loved ones, and human kind. The news of success with a novel technology in putting to rest these diseases brings a purpose in life. Such is the case with Ashanti DeSilva, a four-year-old girl diagnosed with severe combined immune deficiency (Human Gene Therapy). Ashanti hardly lived what would be call a normal life, confined to her sterile home where she battled common childhood diseases, like the cold, with massive amounts of antibiotics. She lived a life of separation, avoiding contact with the public and even those she loved. With a compromised immune system due to a missing gene in her genome, she was vulnerable to every passing germ. On September 14, 1990, Ashanti received a life changing treatment as the first approved gene therapy. In the procedure the researchers removed white blood cells from Ashanti, which were then grown in a lab. These cells were then spliced with the missing gene and infused back into Ashanti. Although this is a treatment and not a cure, Ashanti can now live a life she and her parents dreamed of. She can now attend school and play with friends and family without fear of contact, thereby living a more... ...lt;http://www.wiley.co.uk/genmed/clinical/> Human Gene Therapy (2000). National Reference Center for Bioethics Literature. (Online) 20Nov04. <http://www.georgetown.edu/research/nrcbl/scopenotes/sn24htm>. Questions and Answers About Gene Therapy (1993). National Cancer Institute. (Online) 20Nov04. <http://www.cancernet.nci.nih.gov/clinpdq/therapy/Questions_and_Answers_About_Gene_Therapy.htm>. Rubanyi, G. (2001). The Future of Human Gene Therapy. Molecular Aspects of Medicine. 22,3, pp. 113-142. Walters, LeRoy, and Julie Gage Palmer. Ethics of Human Gene Therapy. Oxford University Press, New York. 1997. Williams, D. (2003). Gene Therapy-New Challenges Ahead. Science. 302, 5644, pp. 400. Wilson, J. (1997) What Is Gene Therapy? The Institute for Human Gene Therapy. (Online) 20Nov04. <http://www.med.upenn.edu/ihgt/info/whatisgt.html>.

Bad corporate governance Essay

Approach Governance Governing is a process of implementing decisions, rules and regulations in a group of people. Its concept has been widely used by companies to make their workers comply a set of agreed actions that were done and ordered by the management. The management’s ways of doing rules and policies has a big effect in a company’s performance as a whole. As decision making is vital to a company, the management should be equipped with the knowledge of how they are going to make their decisions every day. Study of Good and Bad Governance Good Governance Good governance will surely give benefits to the company, employees, customers and suppliers. Its implemented decisions had considered the characteristics of Participation, Rule of Law, Transparency, Responsiveness, Consensus Orientation, Equity and Inclusiveness, Effectiveness and Efficiency and Accountability that if complied well, it will bring good feedbacks and result to the company. Bad Governance Mismanagement has always been a problem in all companies which is a start of bad governance. Bad governance emerges when conflict rises among people who are involved in the company. It includes conflict of interest, political issues among members of the company, social problems, discrimination, lack of participation and more. When employees or the people concerned to the company starts to ask questions about the decision of the company’s management, then there is an unclear part in that certain decisions being implemented that employees do not understand or agreed. Analysis All companies have their different mission and vision as their instrument and inspiration to be the best that they can to survive in a very competitive market. In this paper, we will examine the different possible causes why the UK Industrial Company and MISnet Inc. failed. Sample Study: The UK Industrial Company Failure The UK Industrials is composed of 539 firms and observed from 1988-1993. From table 1, we can see that from the original 539 companies, 56 companies from the group exit the firm because of its financial stabilities. This resulted to shake to the whole company making it like a domino effect to fail the company. The case study made by John Hunter and Natalia Isachenkova for the UK industries explained that the result of the UK Industrial failure is its lack of knowledge in determining the financial stability of the industry which is very important for investment decisions at the micro level. Individuality also played a big part in their failure because the study showed a big evidence of division from different panels as such, decision making regarding the industries financial problem, profits, liquidity, turnovers and changes were greatly affected. Aside from the causes of failure mentioned, the industry is also said to have focused on their current cash flow rather than also thinking about the future economic value of the firm according in their future cash flows.

Fashion And The World Of Fashion - 1087 Words

The world of fashion is always changing and new trends are always emerging. The ways by which trends and fashion news are communicated to the public has evolved as technology advances. Before television and the internet, it was difficult for designers, photographers, and fashion brands alike to spread word about the latest in fashion to a large mass of people. With the help of modern technology, fashion has made its mark in the world by appearing on television networks, online blogs, social media, and digital magazines. In the past, fashion was viewed as something to which only privileged people could have access. It was hard to keep up with trends because it was not mass communicated in the same way that it is today. Fashion shows were the best way to see the newest styles and collections from high-end designers. However, it is difficult do attend these shows because the tickets go to celebrities, socialites, and other prominent people in the fashion world. Harvard professor, Jeanni e Suk, notes that the â€Å"growing ease of travel and communication† has made the dissemination of fashion much easier (Harvard Magazine). Another way fashion was accessible was through magazines. The most common way people stayed caught up with fashion was through magazines because they were affordable and up to date. Suk also employs that the mass production of newspapers and other forms of publication has helped â€Å"fashion trends spread rapidly† (Harvard Magazine). Nowadays, technology isShow MoreRelatedThe World Of Fashion And Publicity1268 Words   |  6 PagesThe world of fashion and publicity has undeniably been enriched by these seemingly expected traits, but to what avail? Tyra Banks, host and judge of the popular reality TV show Americas Next Top Model, is regarded as one of the most beautiful -and successful- women of all time. Her claim to fame began at the age of 15, as her picturesque disposition spread across the covers of GQ, Sports Illustrated, an d Victoria’s Secret. She became an expert and â€Å"model† to the amateurs of the fashion world. InevitablyRead MoreThe Effects Of Fast Fashion On The World1547 Words   |  7 Pages The Effects of Fast Fashion on the World This papers purpose is to teach fashion heavy consumers on the real price of fast fashion and how buying it affects the environment. This type of audience can be anyone who partakes in the buying of well-known cheap retail stores that have a large audience of being fast and obtainable. These consumers should have the information on how fast fashion effects are environment so it could possibly alter their buying habits to be eco-friendlier but buying eitherRead MoreThe Importance of Fashion in the Modern World897 Words   |  4 PagesFashion is something that keeps on changing and because of its change, fashion effects our lives nearly in every aspect like language, furniture, homes, cars, clothes, food and many other things. There are trendsetters and trend followers with different degrees of adaption but here trend is a broader term pertaining to style design, deriving from cultures, social, or many other factors of which fashion is a manifestation. Fashion has become one of the m ost important aspect of life in today’s lifeRead MoreThe Unattainable Standards of the Fashion World1145 Words   |  5 PagesMost people think of the fashion industry as a materialistic world of extravagant, overpriced, un-wearable clothing. Where anorexic, and yet extremely beautiful women use their looks to sell you a product that they themselves probably don’t even like. They think of an industry that sets the most unattainable standards and lowers the self-esteem of young women to zero. They think of it as a world where everyone is judged and no one will ever be pleased†¦and in the end none of it even matters becauseRead MoreHow Elizabethan Fashion Has Influenced the Modern Day Fashion World612 Words   |  3 Pagesgeneration laughs at the old fashions, but follows religiously the new.† (Fashion Quotes 1) The words once spoken by Henry David Thoreau are politically correct. People often look at Elizabethan‘s choice of fashion and ridicule every thing about it from the hair, down to the stockings. As it appears, fashion has always been a broad topic of discussion in the world. Whether it is NY Fashion Week or a Macy’s fashion show, fashion is something that has always been an eye catcher. 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Even though Prada hails from Italy, where family owned companies have strong patriarchal values and hidden agendas, Prada has outgrown most of its competition due to its openness and transparency. Not only that, but Prada has always been in the forefront of using technology to step its game up and thus become a label that directs the fashion world. One such example was when PradaRead MoreZara, The Largest International Fashion Companies Of The World1608 Words   |  7 PagesZara is one of the largest international fashion companies of the world. Founded in 1975 in La Coruà ±a by Amancio Ortega, the company still lives by the simple idea of linking the customer demand to manufacturing, and link manufacturing to distribution. In 1985, Inditex became the holding company of Zara and Jose Maria Castellanos. 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Different Types of Pathogens

Basic Paragraph Structure Comparisons Speech In...

(Basic Paragraph Structure) (TS) The plot is what moves our protagonists story forward as he finds his way in the world. (MP) The battle royal serves as a plot device to the main plot of the protagonist giving his speech. (SS) â€Å"When I got there it was on the occasion of a smoker, and I was told since I was to be there I might as well take part in the battle royal†¦ The battle royal came first.† (Ellison 278). (ES) As a result of his taking part in the battle royal he would be subjected to a naked woman (279 Ellison), electrocution (284 Ellison) and rampant racism (280-285 Ellison). (MP) The main plot of this short story is his journey to give a speech to a group of rich and influential members of the community. (SS) â€Å"I was invited to give†¦show more content†¦(ES) He doesnt know what he wants to do with her perplexed by his inner emotions and feeling as though that only he can protect her from the eyes that surround him. (ES) The white men surrounding them can also be a metaphor for how we feel when we feel this way, looking, and subsequently feeling as though you have done something wrong and not looking and then feeling that temptation arise from within oneself. (ES) She doesnt just affect the protagonist, she also affects societys highest class causing them to go insane over her having given into the vices surrounding them. (MP) The â€Å"gold† coins are symbols of tools used to deceive and lie. (SS) â€Å"But what had excited me, scattered here and there, were the gold pieces.† (Ellison 283) â€Å"I did not even mind when I discovered that the gold pieces I had scrambled for were brass pocket tokens† (Ellison 287).(ES) The brass tokens were simply used to deceive the boys into fighting one another for the pleasure of the white men perversely watching the boys being electrocuted, laughing and enjoying themselves at watching the boys being in pain and desperation.(ES) This was all a lie though to the boys a s the gold coins were actually brass tokens, another way of these white men were appearing to help the boys but in actuality were only helping themselves and causing pain to the black youth. (Basic Paragraph Structure) (TS)Throughout this story multiple themes play at the same

Ebooks Are Inferior to Real Books Free Essays

1. Good evening chairperson, ladies and gentleman. It is one thing to down load an eBooks and read it at your convenience but is this experience the same as lying out on the beach reading the latest publication from your favourite novelist with the worry of the device failing | 2. We will write a custom essay sample on Ebooks Are Inferior to Real Books or any similar topic only for you Order Now Your expensive device may be stolen while you’re in the surf or sand could enter your devices interface. Ladies and Gentlemen reading from an eBook is simply not the same as reading from a physical printed book as all electronic devices are subject to failures. 3. The topic before us this evening is that â€Å"eBooks are inferior to real books† Not one member of the affirmative team will deny that eBooks have been a great innovation however there are many disadvantages associated with the use of eBooks which would support our team’s argument that traditional books are superior and therefore by definition eBooks are inferior. | 4. We as the Affirmative team define eBooks as electronic copies of books, usually read through an e-reader or computer and real books as physical printed paper copies of books. Tonight we will be discussing this on two key levels: I will discuss the social aspects and my second speaker Tom will address the disadvantages of eBooks from an economic perspective. | 5. Firstly I will address the inferior qualities of eBooks with regard to them denigrating the culture of reading and secondly the notion that print books promote a more holistic and equitable circumstance for people to have a greater access to literature both contemporary and traditional. | 6. Now to my first point, addressing print books and their significant contribution towards promoting a culture of reading. E-Readers are far less capable of presenting artistic illustrations in the same capacity as real books. | 7. Very complex, design-heavy books such as comics do not translate well into eBook format, and in many cases people in possession of older e-reader devices, fail to support all of the technologically advanced features that are included within newly released eBooks and e-readers. | 8. Ladies and Gentleman how are we to cultivate a love for books with future generations if all we have access to is unexciting and uninteresting, dull, black and white text. Think of the long held reading traditions which families employ when raising their children. | 9. Young children will always be interested in beautiful three dimensional illustrations adorned in colour and exciting imagery, not walls of text. The artistic value and interactivity of the children’s books we grew up with is something you certainly cannot replicate with an e-reader. | 10. This is a crucial part of the culture of reading that can and will engage our youth in reading from an early age. For centuries book lovers have enjoyed browsing the shelves in a book store, reading the blurbs and thumbing through the illustrations. This is an important part of the culture of reading, a culture promoted by print books and a culture degraded by eBooks. | 11. This is further vindicated as statistics from over 250 000 surveys conducted by Amazon have revealed that 55% precent of e-books purchased from the kindle or amazon online catalogue have been planned purchases and only 5% of buyers have actually browsed the online catalogue like you would in a real bookstore. | 12. Print books are often utilised for decorative purposes in a home. They can define ones interests’ and even a person’s profession, for example doctors and lawyers often have large libraries of books in their homes. Furthermore print books are often culturally and historically significant for various reasons, can form part of collections, or represent sentimental significance. Ebooks do not have that same utility. | 13. According to Jan Noyes and Kate Garland’s scientific report released in 2008 addressing the cognitive advantages and disadvantages of eBooks; it was discovered that screen reading was found to increase stress and exhaustion levels. Finally, the technology of an e-book can also prove to be a disincentive for prospective readers. | 14. Add to these, the health issues of eye strain, the anxiety of worrying about battery life, damaging the screen of a reading device, its lack of portability in extreme or remote environments, problems of viruses and software bugs and the incompatibility of formats across devices are not issues that the reader of traditional books encounter. | 15. RSI and long periods looking at a screen, plus the possibility that an e-book can be hacked and edited so that the original text could be censored or lack authenticity thus creating several more reasons why e-books can turn people off reading. | 16. All of these significant points refer to the culture of reading which is vital to society as we know it. This now brings me to my second argument that print books promote a more holistic and equitable circumstance for people to have a greater access to literature both contemporary and traditional. | 17. EBooks are often a non-inclusive medium as it is a significant financial investment for individuals to purchase an E-reader. It is difficult for people without substantial financial means to make that investment when their primary focus is directed at providing for their families and their needs. | 18. Traditional books are always more accessible to the general public, in many cases through a library. Libraries provide a free and easy way for people of all socio-economic backgrounds to access books of all varieties and in addition libraries can be accessed locally as there is one in most suburbs. 19. Also, opportunities to read are enhanced because books are a tangible asset that can be easily exchanged, passed on from generation to generation and discarded for other people to pick up cheaply at fetes, book fairs and second hand bookshops. | 20. They are also a valuable resource to be collected and donated to institutions, waiting rooms, schools and third world countries. In other wo rds making them accessible to the general population. Ladies and Gentleman you cannot do this with an eBook! | 21. The reliance of e-books on technology conjures the frightening prospect of a world without literature, recorded historical data, in fact, all of the knowledge and entertainment that is currently held in the traditional manuscript of books and digital media. | 22. What happens if the gadgets and software we need to decode e-books malfunctions, there is a lack of electricity or our digital world collapses? We need traditional books to protect future access to reading for everyone. | 23. Tonight Ladies and gentleman I have argued the social aspects of why eBooks are most definitely inferior to real books. 24. My first point tonight detailed how print books significantly contribute towards promoting a culture of reading whereas eBooks damage that culture and my second point addressed how print books, through libraries promote a more holistic and unified circumstance where it is much easier for people who have less, to gain a greater access to more. | 25. Ladies and gentleman when DVDâ₠¬â„¢s came out people thought that would be the end of cinema. There will always be a place for real books and if eBooks are such remarkable products why are we still publishing books? Comparing e-readers to books is similar to comparing a modern contemporary rock song to a cover, which is never as good as the original. | 26. Every now and again you might get a cover version of a song that is perceived as better than the original but generally speaking more often than not the cover is never as good as the original. You can manipulate it and improve it but when it all comes down to the crunch it is the original that stands the test of time. The same is true for the traditional book which will pass the test of time. | How to cite Ebooks Are Inferior to Real Books, Essay examples

Evil In Dante And Chaucer Essay Example For Students

Evil In Dante And Chaucer Essay We in the twentieth century would be much more hard-pressed to define evil than would people of either Chaucers or Dantes time. Medieval Christians would have a source for it Satan and if could easily devise a series of ecclesiastical checklists to test its presence and its power. In our secular world, evil has come down to something that hurts people for no explicable reason: the bombing of the Federal Building in Oklahoma City, the burning of black churches in the South. We have taken evil out of the hands of Satan, and placed it in the hands of man. In doing so, we have made it less absolute, and in many ways less real. Nonetheless, it must be recognized that in earlier times evil was not only real but palpable. This paper will look at evil as it is portrayed in two different works Dantes Divine Comedy, and Chaucers Canterbury Tales and analyze what the nature of evil meant to each of these authors. The Divine Comedy is an epic poem in which the author, Dante, takes a visionary journey through Hell, Purgatory, and Paradise. The purpose of Dantes visit to Hell is to learn about the true nature of evil. He is guided in this journey by the ghost of the Roman classical poet Virgil, who, as wise in the ways of the spirit as he may be, cannot go to Heaven because he is not a Christian. Virgils experience in the underworld, however, make him an authority on its structure, and he is more than willing to share his knowledge with Dante in order that Dante might return to life and share his revelations with others. In Hell Dante is presented with insight into the nature of evil, which, he is told, has to be seen and experienced to be understood. At any rate, only after having looked the Devil in the face and seen for himself the horror, the stupidity, and the self-destructiveness of Hell, is Dante ready to move out of the Inferno and back up toward the light of Gods love. Dante conceived of Hell as a cone-shaped hole, terraced into seven concentric rings. The uppermost level, Limbus, actually is not a Hell at all, but merely an abode for good people born into the culture of Christianity but who themselves had never been baptized, as well as those born before the time of Christ. Below Limbus, however, the rings of Hell yawn deeper and deeper, and the torments grow more severe, ending at the bottom with a frozen lake which is the abode of Satan himself. Each different type of sin merits its own ring. The unfortunate inhabitants of each ring and pouch and section of Hell receive a different